Anaerobic bacteria named as acetogens have been shown to ferment gases such as CO and CO2 plus H2 into chemicals (acetate, ethanol, lactate, 2,3-BDO, etc.) through the acetyl-CoA pathway. Depending on the composition of the C1 gases and particularly depending of the CO content of syngas, some bacteria can be more efficient to produce acetate. In this context, metabolic engineering and synthetic biology are powerful tools to increase the acetate production and reduce the spectrum of unwanted by-products.
CO2SMOS proposes two routes to optimize the productivity of the CO2 to C2-C4 compounds:
- Tech 1.1: Biotransformation of CO2 into acetate
- Tech 1.2: Biotransformation of CO2 derived syngas into C2 (acetate) and C4 (2,3 BDO) compounds